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Anaferon

Anaferon belongs to the group of immunomodulators and antiviral agents. The drug exerts dual action, that is, early antiviral action mediated through the induction of IFN-α and complementary antiviral аnd full-scale immunomodulatory effects that are realized via IFN-γ production.

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O. I. EPSTEIN
ULTRALOW DOSES
(HISTORY OF ONE RESEARCH)

This monograph is devoted to a systemic study of the effects of potentiated (activated) preparations that contain an active substance in ultralow concentrations. The activated preparations were shown to have previously unknown modifying properties. Taking into account these data, a new class of medical products (antibodies in ultralow doses) was developed. A new direction of bipathic pharmacotherapy was proposed. The first part of this monograph not only illustrates the results of our studies, but also describes the physiological and physical aspects and world outlook of ultralow doses. The final chapters are devoted to experimental and clinical pharmacology of antibodies in ultralow doses. The monograph is addressed to physicians of various specialties.

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A randomized, open-label, comparative, 6-month trial of oral ultra-low doses of antibodies to tumor necrosis factor-α and diclofenac in rheumatoid arthritis. Dudina J.L, Petrov V.I., Babayeva A.R., Martyushev-Poklad A.V., Tcherevkova E.V., Epstein O.I., Sergeeva S.A

Antibodies to S100 proteins have anxiolytic-like activity at ultra-low doses in the adult rat. Vinsent Castagne, Martin Lemaire, Irina Kheyfets, julia L. Dugina, Svetlana A. Sergeeva, Oleg I. Epstein

Sildenafil and a Compound Stimulating Endothelial NO Synthase Modify Sexual Incentive Motivation and Copulatory Behavior in Male Wistar and Fisher 344 Rats. Xi Chu, Ekaterina S. Zhavbert, Julia L. Dugina, Irina A. Kheyfets, Svetlana A. Sergeeva, Oleg I. Epstein, Anders Agmo

Sexual incentive motivation in old male rats: The effects of sildenafil and a compound (Impaza) stimulating endothelial NO synthase. Xi Chu a, Anders Agmo

Membrane and synaptic effects of anti-S-100 are prevented by the same antibodies in low concentrations. Epstein O.I., Beregovoy N.A., Sorokina N.S., Starostina M.V., Shtark M.B., Gainutdinov Kh.L., Gainutdinovf T.Kh., Muhamedshina D.I.

Improvement of Memory by Means of Ultra-Low Doses of Antibodies to S-100B Antigen. Epstein O.I., Pavlov I.F. and Shtark M.B.